High Security Animal Disease Laboratory

Indian Veterinary Research Institute, Indian Council of Agricultural Research

 
 
 
 
 

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Training cum workshop on 'Conventional and Molecular techniques for diagnosis of trans-boundary animal diseases', Phase 1: 18-25 February, 2014; Phase 2: 28 Feb - 7 March, 2014 at HSADL, IVRI, Bhopal.

 

International Biosafety Awareness Programme including Workshop on “Culture of Responsibility” on 11th January, 2014 at HSADL, IVRI, Bhopal.

 

Regional Training Programme for SAARC member countries on "Molecular Techniques in Diagnosis of Diseases of Farm Animals and Poultry" from 22nd April to 1st May 2013, at HSADL, IVRI, Bhopal.

 

Hands-on training program on 'Laboratory Diagnosis of Avian influenza' from 12th to 15th September 2012 at HSADL, Bhopal.

 

Hon’ble Deputy Director General (Animal Sciences),  Dr. K. M. L Pathak's visit to HSADL on 19th November 2011.

 

Farewell to the Joint Director Dr. S. C. Dubey on 31st October 2011.

 

ICAR short course on Molecular Approaches for Laboratory Diagnosis of Bovine Viral Diarrhoea Virus (BVDV) from 07-16 September, 2011 at HSADL, Bhopal.

- Inaugural session

- Valedictory session

Agriculture Minister's visit to HSADL on 1st September 2011

WHO workshop on Laboratory Biosafety and Biosecurity organised from 17th to 19th August 2011 at HSADL, Bhopal

Training on Working in Biosafety Laboratory orgainsed from  4th - 10th February 2011 at HSADL, Bhopal

Brainstorming session on “Research priorities of HSADL for the next decade”  organised on 1st December 2010, at HSADL Bhopal.

Top Agriculture Institutes Awarded with ICAR Awards....Scientists and Farmers among Awardees

Confusion between Swine flu in pigs and pandemic H1N1 in humans

HSADL gets international recognition as reference laboratory for bird flu

 

 

 

International Biosafety Awareness Programme including Workshop on “Culture of Responsibility” on 11th January, 2014 at HSADL, IVRI, Bhopal.

An one day International Biosafety Awareness Programme including Workshop on “Culture of Responsibility” was organized by Society for Biosafety, India in collaboration with ICAR and American Society for Microbiology at High Security Animal Disease Laboratory, IVRI, ICAR on 11th January, 2014. The program was specially intended to create an awareness of the concept of biosafety including laboratory worker’s safety, environmental protection and conduct of dual purpose research with responsibility. A total of 92 participants from various organizations such as ICAR, ICMR, DADF, Universities and colleges participated in the training program. Dr. Sandeep Bhatia, Organizing Secretary warmly welcomed the participants. Dr. D. D. Kulkarni, Principal Scientist and in-charge Joint Director, HSADL and President, SBS gave a brief background regarding the genesis and purpose of the workshop. The program included two lectures by Dr. H. V. Murugkar and Dr. Sandeep Bhatia, Principal scientists of HSADL, three video modules covering various aspects of biosafety kindly provided by American Society for Microbiology and visit to engineering division of HSADL. Dr. H. V. Murugkar and Dr. Sandeep Bhatia also moderated the discussions during the video module presentations. The pre and post assessment reports of the participants revealed that the workshop could fulfil its objectives. Dr. D. D. Kulkarni presented the certificates to the participants and the program ended with the vote of thanks address from Dr. Richa Sood, Co-organizing secretary.

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 Hands-on training program on “Laboratory Diagnosis of Avian Influenza” from 12th to 15th September, 2012

A four day Hands-on training program on “Laboratory Diagnosis of Avian Influenza” from 12th to 15th September, 2012 sponsored by Department of Animal Husbandry, Dairying and Fisheries, Ministry of Agriculture, Government of India under CDDL grant was organized at High Security Animal Disease Laboratory, IVRI, ICAR. The training program was specially meant for giving hands-on training to scientists of Regional Disease Diagnostic Laboratories (RDDLs). A total of six scientists viz. Dr. Gajendragad, Principal Scientist of PDADMAS, Bangaluru, Dr. Shamindra Nath Sarkar of ERDDL, Kolkata, Dr. Anil Gupat of RDDL, Jalandhar, Dr. Barnalee Saikia of NERDDL, Guwahati, Dr. Sadhna Firke of WRDDL, Pune and Dr. Sanjeev Kumar of IAH&VB, SRDDL, Bangaluru participated in the training program. During the informal inauguration program, Dr. J. M. Kataria, Joint Director, HSADL and Course Director of the program welcomed the participants and Dr. D. D. Kulkarni, Principal Scientist and in-charge HRD gave a background regarding the genesis of the training program. The training program included two lectures and hands-on training on diagnosis of avian influenza. The participants were also introduced to the concepts of biosafety and bioengineering by the biosafety officers and engineers of HSADL. Dr. Nagarajan, Scientist (SS) who was the course coordinator, coordinated the training program under overall supervision of Dr. J. M. Kataria. The feedback reports from the participants revealed that the training program could fulfill its objectives. At a simple valedictory function held at the end of the training program, Dr. D. D. Kulkarni presented the certificates to the participants and the program ended with the vote of thanks address from Dr. S. Nagarajan.

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Hon’ble Deputy Director General (Animal Sciences) Dr. K.M.L. Pathak's visit to HSADL on 19th November 2011

Hon’ble Deputy Director General (Animal Sciences) Dr. K.M.L. Pathak visited High Security Animal Disease Laboratory (IVRI) at Bhopal on 19th Nov., 2011. He was welcomed with bouquet of flowers by Dr. H. V. Murugkar, Senior Scientist officiating as Joint Director and other scientists and staff of HSADL. Dr. S. Nagarajan, Incharge of Technical Cell apprised Hon’ble DDG about activities of HSADL. Dr. Pathak   appreciated the achievements of HSADL scientists and emphasized the need to carry out research programs in a multidisciplinary approach and appealed the HSADL scientists to come out with better research output than before. He assured the regular availability of funds to HSADL for creating new infrastructure, routine operation and maintenance of the lab and for the research contingency. He expressed his gratitude towards services of former Joint Director Dr. S. C. Dubey who was present in the meeting on DDG’s request. Dr. Dubey who recently retired on 31st Oct., 2011, has served as Joint Director of HSADL for four and a half years since May, 2007. Dr. Pathak requested Dr. Dubey to remain associated with activities of HSADL and help young scientists in achieving higher goals in research and act as their guiding source. 

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Farewell to Joint Director Dr. S. C. Dubey on 31st October 2011

 

Dr. D. D. Kulkarni taking charge as Joint Director from Dr. S. C. Dubey.

 

Administrative officer Shri. S. K. Gupta presenting memento to Dr. S. C. Dubey.

Staff welfare committee of HSADL, organised a grand farewell party for Joint Director Dr. S. C. Dubey who retired from Agricultural Research Services of ICAR on 31st Oct., 2011. Dr. Dubey joined ICAR in 7th March 1976. During his service of 35 years he served at HSADL two times, first as Senior Scientist and Principal Scientist from 7th Aug 1991 to 27th Oct 1999 and second as Joint Director of HSADL from 10th May, 2007 to 31st Oct, 2011. The Scientists and Staff members praised his contribution in bringing HSADL into limelight and develop international linkages. During his tenure as Joint Director, HSADL, he pursued the proposal for international recognition of HSADL by OIE leading to recognition of HSADL as OIE Reference Laboratory for AI. He also developed linkages with FAO, WHO, SEPRL, USA and AAHL, Australia. He initiated the proposal for new laboratory (BSL-2 integrated with BSL4) at HSADL which is soon going to materialize in the next five year plan. His techno-managerial interventions led to better utilization of containment facility for handling of exotic diseases and emergence of HSADL as focal point for capacity building activities. He initiated revenue generation through diagnostic services, conducted training programs on diagnosis and control of exotic diseases in liaison with various international and national agencies such as FAO, DADF, VCI and State A.H. departments. He revived IBSC and IAEC and was instrumental in implementation of CPCSEA and Animal Welfare Board regulations recognized in upcoming animal experimental facilities. He initiated development of database management for Avian Influenza.

Dr. S. C. Dubey was given farewell by bouquet and garland of flowers. Presentation of gift was solicited by the administrative officer Mr. S. K. Gupta. A small party was arranged in his honour.

 

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ICAR short course on Molecular Approaches for Laboratory Diagnosis of Bovine Viral Diarrhoea Virus (BVDV) from 07-16 September, 2011 at HSADL, Bhopal .

Inaugural Session

A function was organized at the High Security Animal Disease Laboratory (HSADL), Bhopal to inaugurate an ICAR sponsored short course on ‘Molecular Approaches for Laboratory Diagnosis of Bovine Viral Diarrhoea Virus (BVDV)’, to be conducted at HSADL from 7th to 16th September, 2011. Dr. Akhilesh Pandey, Chairman, Madhya Pradesh Private Universities Regulatory Council (MPPURC) was the chief guest on the occasion. In his inaugural address, Dr. Pandey quoted that the facilities at HSADL are amongst the best in Asia and also emphasized the need for newer and more sensitive diagnostic approaches for detection of microbial infections including latent viral infections. Dr. S. C. Dubey, Joint Director, HSADL welcomed the participants of the short course and addressed the gathering.  Dr. N. Mishra, Course Director briefed about progress of Pestivirus research at HSADL since its inception. During this short course, sixteen participants from various Research Institutions, Veterinary Colleges, State and regional disease investigation laboratories, Animal Husbandry Departments across the country will undergo hands-on training on the latest molecular diagnostic tests for detection and differentiation of pestiviral infections of ruminants. This programme will also facilitate scientific interactions and increase the general awareness about one of the most complex emerging viral diseases of livestock in our country.

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Valedictory session  

A valedictory function was held at the High Security Animal Disease Laboratory (HSADL), Bhopal to conclude the ICAR sponsored short course on ‘Molecular Approaches for Laboratory Diagnosis of Bovine Viral Diarrhoea Virus (BVDV)’, organized at HSADL from 7 - 16th September, 2011. Dr. Kusumakar Sharma, Asst. Director General (HRD), ICAR, New Delhi was the chief guest on the occasion. Dr. S. C. Dubey, Joint Director, HSADL welcomed the Chief Guest and introduced the participants. Dr. N. Mishra, Course Director, delivered final report of the short course. Dr. Sharma congratulated the faculty of the short course for successful organization of the short course. He also elaborated various schemes of Education Division of ICAR proposed in the 12th plan for capacity building measures in agricultural research and education in the country. Representatives from participants, Dr. Jhala, Professor  & Head, Anand Veterinary College and Dr. Varsha Sharma, Associate Professor, Jabalpur Veterinary College shared their experiences and appreciated the HSADL team for their excellent organization of the training programme. During the past ten days, sixteen participants from various Research Institutions, Veterinary Colleges, State and regional disease investigation laboratories, Animal Husbandry Departments across the country underwent hands-on training on conventional as well as latest molecular diagnostic tests for detection and differentiation of pestivirus infections of ruminants. This programme also was a platform for scientific interactions between the diverse group of participants and faculty. The function ended with vote of thanks address from Dr. D. D. Kulkarni, Principal Scientist, HSADL.

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Agriculture Minister's visit to HSADL

Minister of State for Agriculture and Food Processing Dr. Charan Das Mahantji visited the High Security Animal Disease Laboratory of ICAR on 1st Sept., 2011. Various dignitaries from State and Central govt. were present at this occasion including Private Secretary to the MoS, Mr. V. K. Dewangan. During his visit the Hon’ble Minister was shown various bio-engineering components of the BSL-IV lab by Dr. S C Dubey, Joint Director of HSADL. In his welcome address Dr. Dubey gave a brief introduction of the functioning of HSADL and put before the Minister certain problems faced by the lab. The Hon’ble Minister Dr. Charan Das Mahant appreciated the role of ICAR in ushering Green Revolution and subsequent developments in agriculture in India through its research and technology development that has enabled the country to increase the production of food grains by 4 times, horticultural crops by 6 times, fish by 9 times (marine 5 times and inland 17 times), milk 6 times and eggs 27 times since 1950-51, thus making a visible impact on the national food and nutritional security. 

He appreciated the efforts of the whole team of HSADL in keeping the country away from exotic and emerging diseases including the bird flu which has been a problem for poultry sector for last 4-5 years. He stressed the need to extend the benefits of the agricultural research to farmers and appealed the scientists to give major emphasis on “Lab-to-land” program. He made a special mention of threat of bio-warfare and emphasized the need to have full preparedness by HSADL. The Minister agreed that there is need to give better support to the lab in terms of manpower and financial support for building new infrastructure as well as maintaining the existing ones in the bio-containment lab.

Various dignitaries including Directors of CIAE and IISS, their scientists, officials from State Animal Husbandry Department and other officials from State Government were also present at this function.

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WHO workshop on Laboratory Biosafety and Biosecurity

A three day workshop on "Laboratory Biosafety and Biosecurity" from 17th to 19th August, 2011 was organized at High Security Animal Disease Laboratory, IVRI, ICAR. The workshop was sponsored by WHO, India Office, New Delhi. Dr. S. C. Dubey, Joint Director, HSADL welcomed the participants and the experts and gave a background regarding the genesis of this important area of the workshop. Dr. Dubey told that the enormous response and appreciation of the previous workshop held in November, 2009 made it possible to organize another workshop this year and was an attempt towards need of increased awareness about the laboratory biosafety and biosecurity in the present era of increasing threat of newly emerging health problems of human and animals.               

Dr. H.K. Pradhan, WHO consultant, India office briefed the participants about the programme highlights. Foreign biosafety experts Dr. Michael Johnson from IAH, Pirbright Laboratory, UK and Dr. Guus Koch from Lelystaad Lab, The Netherlands shared their knowledge and expertise with the participants. A number of senior professionals from medical institutes such as IVRI, Bangalore, VP Chest Institute, New Delhi, PGI, Chandigarh, JLN institute of PG Medical Education & Research, Puducherry, JALMA, Agra, Lady Hardinge Medical College, New Delhi, School of Tropical Medicine, Kolkata and DRDO, Gwalior and veterinary institutes such as IVRI, Bangalore, GADVASU, Ludhiana, IGKV, Raipur, VTCC, Hisar, CSWRI, Avikanagar, NRC Equines, Hisar, DADF, MoA,, GoI, PDFMD, Mukteshwar and MP state veterinary department participated in the workshop to get exposure of the field of biosafety with lectures from the experts on the areas such as, Risk assessment for the organisms to be handled in the containment laboratory, good microbial techniques in containment laboratories, design and validation of facilities in containment laboratories, operation and maintenance of containment laboratory and programmes, use of biosafety equipment including biosafety cabinets, animal biosafety, laboratory maintenance and cleaning procedures, laboratory waste and handling procedures, packaging and transport of materials from containment laboratories,  emergency procedures in containment laboratory, etc. In addition to the classroom activities, the participants were exposed to the various practical aspects of the maintenance and functioning of the biocontainment laboratories through practical demonstrations and visits inside the biocontainment laboratory. Post workshop evaluation and feedback reports from the participants were sought whose analyses revealed the usefulness of the training programme.

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Training on Working in Biosafety Laboratory from 04-10 Feb 2011 at HSADL Bhopal.

A week-long training on Working in Biosafety Laboratory was especially organized for the Veterinary officials of the Institute of Animal Health and Veterinary Biologicals, Southern Regional Disease Diagnostic Laboratory, Hebbal, Bangalore. With rising awareness about laboratory biosafety and upcoming biosafety labs in State Veterinary Units, there is increasing demand for training in this area. The High Security Animal Disease Lab being the first BSL-IV lab in India working smoothly since year 2000 has accumulated significant expertise in the area of biosafety over the years of its working and is therefore facilitating other organizations in this area for their training needs and consultation. The training included lectures on different aspects of biosafety eg. bio-engineering, biosafety practices in BSL, decontamination procedures, safe-handling of high risk pathogens, animal biosafety and use of biosafety cabinets. The lectures were followed by practical demonstration of various biosafety procedures and protocols for working in biosafety lab. The program was marked by the expert participation of Indian representatives of USA’s Biosafety Enhancement Program (BEP) Dr. Suman Paranjpe and Dr. David Franz on first day and Dr. A. K. Sinha, Scientist, National Disaster Management Authority on the concluding day of the training. Dr. Richa Sood, Scientitst and Asstt. Biosafety Officer coordinated the training under overall supervision of Course coordinator and Joint Director Dr. S. C. Dubey.

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Brainstorming session on “Research priorities of HSADL for the next decade”  organised on 1st December 2010, at HSADL Bhopal.

The High Security Animal Disease Laboratory of ICAR (Indian Council for Agricultural Research) organized a Brainstorming Session on “Research priorities of HSADL for the next decade” in collaboration with "Society for Biosafety" on 1st December, 2010. The Deputy Director General (Animal Sciences), ICAR, Dr. K. M. L. Pathak was the chief guest on this occasion and, Dr. M. C. Sharma, Director IVRI presided over the function. Various dignitaries and resource persons including eminent scientists, university teachers, planners and officials from national and international organizations interacted on various aspects of exotic and emerging diseases of livestock and poultry to prioritize the research activities of HSADL for the coming decade with special emphasis on diseases of national importance. Dr. S. C. Dubey, Joint Director of HSADL presented the national scenario of exotic and emerging diseases of animals. Dr. Leo Loth, FAO representative gave a presentation on regional scenario of the livestock and poultry diseases in the Indian sub-continent. In his inaugural speech, Dr. Pathak, DDG (AS) ICAR, while lauding the work carried out at HSADL, announced that all the monetary assistance for development of BSL-IV laboratory at HSADL will be provided for carrying out work on high risk pathogen in the laboratory.  Dr. M.C. Sharma, Director, IVRI, congratulated Dr. Dubey and his team of scientists for organizing this meet which was a follow up of the suggestions provided during the Institute Research committee meeting held at IVRI, Bareilly in July, 2010. Guest of Honour Dr. Gaya Prasad, ADG (AH), ICAR stressed the need for developing preparedness against a most of exotic and emerging pathogens of the country and emphasized the role of HSADL in taking up these challenges.   

The lab has been in the lime light since it first diagnosed bird flu in poultry in 2006 in Maharashtra followed by incidences of the disease in a few more states of the country. The diagnostic and technical support by HSADL to the Animal Husbandry Department for effective control of bird flu in India has been praised by many international organization including FAO and the World’s apex body for animal health, OIE which has recognized HSADL as one the nine reference laboratories for avian influenza (bird flu).  The deliberations during the meeting will help in carving out a roadmap for HSADL for the next decade to focus its efforts towards emerging disease threats of livestock and poultry like bird flu.

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Top Agriculture Institutes Awarded with ICAR Awards - Scientists and Farmers among Awardees.

New Delhi, 15-16 July, 2010

Shri Sharad Pawar, the Minister of Agriculture, Consumer Affairs, Food and public Distribution, honoured selected scientists, researchers, institutions and farmers for their outstanding contribution in the field of agriculture, with Indian Council of Agricultural Research (ICAR) awards. Minister of State for Agriculture, Consumer Affairs, Food and public Distribution, Prof. KV Thomas and eminent agricultural scientist and Member of Rajya Sabha, Dr. M. S. Swaminathan also addressed the gathering.

This year, 135 awardees under 11 different categories were selected, comprising 5 institutions, 127 scientists and 3 farmers. Out of 127 scientists, 11 are women. Among the State Agricultural Universities and Deemed Universities, the Best Institution Award has gone to the Indian Veterinary Research Institute, Izatnagar. The major accomplishments of the IVRI include recognition of High Security Animal Disease Laboratory (HSADL), Bhopal, as OIE approved reference laboratory, seventh in the world, for highly pathogenic avian influenza diagnosis.

(Edited version from www.icar.org)

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Confusion between Swine flu in pigs and pandemic H1N1 in humans:

Press release

Influenza viruses infecting humans, poultry and pigs.

  • Pandemic influenza H1N1 2009 (WHO) is the name given by the international organizations to the virus that emerged in form of pandemic in 2009 from Mexico that spread to US and then to the other parts of the world. As a misnomer, this viral infection of human being is commonly called “Swine flu” by media. Hence, there is need to use correct name as Pandemic influenza H1N1 2009 (pH1N1 2009).

  • Swine flu (name) should not be used to address the pH1N1 2009 or classical human H1N1 virus.

  • Swine influenza infection (H1N1, H2N2 and H3N2) is a common infection of pigs leading to very mild respiratory illness with self recovery within a short period. Infection from these viruses in pig population has been reported from many parts of the world and has also been detected in Indian native pigs from Tamil Nadu during the surveillance carried out by HSADL scientists during 2009-10 and two isolations of this virus strain has been made. This infection (swine influenza) is in no way connected to the pH1N1 2009 and is neither a risk to human health nor a serious disease of pigs.

  • Classical human influenza H1N1 is also different from the pH1N1 2009 and produces mild to moderate infection in human beings. This virus is also different from swine influenza virus H1N1.

  • Bird flu virus or Highly Pathogenic Avian Influenza H5N1 virus mainly infects poultry and other birds and sometimes also infects humans in contact with the infected poultry. No human case of bird flu has been confirmed so far in India.

 This clarification is being prepared for the media to educate regarding these three influenza viruses and with request to use correct nomenclature during reporting to avoid unnecessary confusion and panic.

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HSADL gets international recognition as reference laboratory for bird flu.

 The long-awaited recognition for High Security Animal Disease Laboratory by Office International Epizooties (OIE) the world's apex organization for Animal Health came into effect at the OIE's headquarter at its 77th General Session held at Paris on 28th May, 2009. Dr. S. C. Dubey gave this news following his return from Paris. With this event, HSADL becomes the third OIE-recognized reference lab for avian influenza in Asia after Japan and China and 9th in the world.


The efforts for getting this recognition started in 2006 when HSADL successfully and promptly diagnosed the first event of bird flu outbreak in Maharashtra and its results were accepted by OIE. An important breakthrough was achieved during Dr. Dubey's visit to Japan last year when he attended OIE-JTF (Japan Trust Fund) meeting and presented the contributions of HSADL for bird flu diagnosis and control followed by proposal for sharing of HSADL facilities for AI control program with other South Asian countries. Later in 2008, Dr. Dubey was invited by FAO-OIE-WHO joint symposia for human-animal interface meeting on avian influenza at Verona, Italy where he again presented country's success story in control of bird flu in India using its own facilities, expertise and resources. After this visit to Italy, HSADL got the informal approval as OIE referral laboratory for avian influenza subject to final approval by general session of the OIE. These two opportunities attracted the attention of world authorities and finally led to the formal approval of HSADL as reference lab by OIE last week. The OIE General Session during 24-29 May, 2009 at Paris, France was marked by the presence of delegates and participants from 174 countries who finalized the revised report of terrestrial code for animal health for global trade of animals and their products. It is worth to mention that OIE acts as an apex organization to formulate & circulate regulatory guidelines for these purposes.



HSADL is at present collaborated with one of the OIE recognized Avian Influenza laboratory in USA at Athens in Georgia on development of new generation vaccines and diagnostics for avian influenza. One of the senior scientist, Dr. David L. Suarez, from the US based South East Poultry Research Lab (SEPRL) visited at HSADL recently for to finalize the project program with HSADL scientists. With status of OIE reference laboratory, HSADL is likely to have similar upward linkages with other OIE recognized labs in frontier areas of bird flu research and participation with OFFLU (OIE-FAO common platform to handle influenza on global basis). Simultaneously, this lab will initiate downward linkages with neighboring countries not having up-to-date facilities for bird flu diagnosis. As a beginning, FAO, VCI (Veterinary Council of India), DADF (Department of Animal Husbandry, Dairying and Fisheries) and SAARC Secretariat sponsored training programs on AI diagnosis for candidates from Nepal, Myanmar, SriLanka and Bangladesh are already being taken up at HSADL.

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